Thursday 21 August 2014

What happens when you survive Ebola

(CNN) -- Two American missionaries infected
with the deadly Ebola virus were given an
experimental drug.
Shortly after, Dr. Kent Brantly and Nancy Writebol
were flown separately from Liberia to Atlanta's
Emory University Hospital -- the first human
patients with Ebola to ever come to the United
States.
Writebol was released from the hospital Tuesday.
On Thursday morning, Brantly walked out of that
same hospital with no signs of the virus in his
system, doctors say.
Their recoveries seem to offer hope for those
fighting the largest Ebola outbreak in known
history. More than 2,400 people have been
infected by the virus, according to the World
Health Organization, and it's killed more than
half.
But ZMapp is not an approved
treatment for Ebola; in fact, no
approved, proven treatment exists. So
governments, aid organizations and
scientists around the globe are racing
to find a way to stop the virus.
Here are answers to questions about
Ebola patients and treatments for the
disease.
1. Are Brantly and Writebol cured?
Mostly. For Ebola patients to leave
isolation, two blood tests had to come
back negative for the Ebola virus. So
their bodily fluids, like blood, sweat
and feces, are no longer infectious.
"Nancy is free of the virus, but the
lingering effects of the battle have left
her in a significantly weakened
condition," Writebol's husband, David
Writebol, said in a statement.
Some doctors believe the virus can
remain in vaginal fluid and semen for
up to several months, according to
WHO. Dr. Bruce Ribner, an infectious
disease specialist at Emory, said there
is no evidence Ebola has ever been
transmitted this way, but the risk was
discussed with both patients.
2. Are they now immune to Ebola?
Doctors believe surviving Ebola leaves you
immune to future infection. Scientists have found
that people who survive Ebola have antibodies in
their blood that would provide protection against
that strain of the virus in the future, and possibly
against other strains as well.
But, as you can imagine, they haven't tested this
theory by infecting survivors with the virus again.
There are four Ebola strains known to infect
humans; the Zaire ebolavirus causing the current
outbreak is the most common.
3. Who else has been given ZMapp?
The Ebola drug was flown to Spain to give to a
priest named Miguel Pajares, who had contracted
the virus in Liberia. Pajares died on August 12.
It's unclear if he was given the drug before he
died.
ZMapp appears to be helping three Liberian
health care workers who were given the
experimental drug. They have shown "very
positive signs of recovery," the Liberian Ministry
of Health said earlier this week . Medical
professionals treating the workers have called
their progress "remarkable."
4. Who makes the drug?
The drug was developed by the biotech firm Mapp
Biopharmaceutical Inc., which is based in San
Diego. The company was founded in 2003 "to
develop novel pharmaceuticals for the prevention
and treatment of infectious diseases, focusing on
unmet needs in global health and biodefense,"
according to its website .
Mapp Biopharmaceutical has been working with
the National Institutes of Health and the Defense
Threat Reduction Agency, an arm of the military
responsible for countering weapons of mass
destruction, to develop an Ebola treatment for
several years.
5. How does ZMapp work?
Antibodies are proteins used by the immune
system to mark and destroy foreign, or harmful,
cells. A monoclonal antibody is similar, except
it's engineered in a lab so it will attach to specific
parts of a dangerous cell, according to the Mayo
Clinic , mimicking your immune system's natural
response. Monoclonal antibodies are used to treat
many different types of conditions.
Sources told CNN the medicine given to Brantly
and Writebol abroad was a three-mouse
monoclonal antibody, meaning that mice were
exposed to fragments of the Ebola virus, and then
the antibodies generated within the mice's blood
were harvested to create the medicine.
However, the drug can also be produced with
proteins made from tobacco plants. ZMapp
manufacturer Kentucky BioProcessing in
Owensboro provided limited quantities of this kind
of the drug to Emory, according to company
spokesman David Howard.
6. Did doctors know it would work in humans?
No. The drug had shown promise in primates, but
even in those experiments, just eight monkeys
received the treatment. In any case, the human
immune system can react differently than
primates', which is why drugs are required to
undergo human clinical trials before being
approved by government agencies for widespread
use.
These cases will be studied further to determine
how the drug worked with their immune systems.
7. Are there other Ebola treatments out there?
Several experimental drugs are in development,
but none has been effective in humans.
The market for these drugs is small -- Ebola is a
rare disease, almost completely confined to poor
countries -- so funding for drug development has
come largely from government agencies.
In March, the NIH awarded a five-year, $28
million grant to establish a collaboration between
researchers from 15 institutions who were
working to fight Ebola. On Wednesday, Wellcome
Trust and the United Kingdom's Department for
International Development announced money for
Ebola research will be made available from a
$10.8 million initiative .
8. Will ZMapp or these other drugs be given to
more Ebola patients?
An ethics panel convened by the World Health
Organization concluded it is ethical to give
experimental drugs during an outbreak as large
as this one, but that doesn't mean it will happen.
Rolling out an untested drug during a massive
outbreak would be very difficult, Doctors Without
Borders says. Experimental drugs typically are not
mass-produced, and tracking the success of such
a drug, if used, would require extra medical staff
where resources are already scarce.
In an opinion article published in the journal
Nature this week, epidemiologist Oliver Brady
says up to 30,000 people in West Africa would
have so far required treatment in this outbreak if
it was available.
9. What about an Ebola vaccine?
For the record, "vaccine" and "treatment" are not
interchangeable terms. A vaccine is given to
prevent infection, whereas treatment generally
refers to a drug given to a patient who has
developed symptoms.
There are several Ebola vaccines in development.
The Canadian government has donated between
800 and 1,000 doses of an experimental Ebola
vaccine to WHO. The drug, called VSV-EBOV, is
Canadian-made and owned, having been
developed by the National Microbiology
Laboratory.
It's never been tested on humans "but has shown
promise in animal research," the agency says. We
don't know if the vaccine has been given to
anyone on the ground.

"Miraculous day" as American Ebola patients released

(CNN) -- Dr. Kent Brantly walked around the
room at Emory University Hospital on Thursday,
hugging staff members and shaking hands.
It was like he wanted everyone to know: I'm no
longer infectious. The virus is out of my system.
Ebola didn't beat me.
Brantly and Nancy Writebol, another American
missionary infected with Ebola in Liberia, have
been discharged from the hospital. Writebol was
released Tuesday and is choosing not to make
public comments, according to the hospital.
"Today is a miraculous day," Brantly said at a
news conference Thursday. "I am thrilled to be
alive, to be well and to be reunited with my
family."
What happens when you survive
Ebola?
Emory's staff is confident that the
American patients' discharges pose
"no public health threat," said Dr.
Bruce Ribner, director of Emory's
Infectious Disease Unit. He said the
reason the public was not made
aware of Writebol's release
immediately was that she requested
her discharge not be publicly
announced.
"Nancy is free of the virus, but the
lingering effects of the battle have left
her in a significantly weakened
condition," her husband, David
Writebol, said in a statement. "Thus,
we decided it would be best to leave
the hospital privately to be able to
give her the rest and recuperation she
needs at this time."
But Brantly passed along gratitude
from the woman with whom he has
shared a harrowing journey.
Both patients were evacuated from
Liberia this month, in a plane specially
equipped with an isolation tent, and
accompanied by medical staff outfitted
in head-to-foot protective clothing.
The plane was able to take only one patient at a
time and made two trips. The patients were taken
to an isolation unit at Emory, where they'd been
treated for the last few weeks.
As she walked out of her isolation room Tuesday,
Brantly recalls Writebol saying, "To God be the
glory."
"We are tremendously pleased with Dr. Brantly
and Mrs. Writebol's recovery," Ribner said at the
news conference. "What we learned in caring for
them will help advance the world's understanding
of how to treat Ebola infections and help,
hopefully, to improve survival" in other parts of
the world.
"There may be some recovery time because this
is a fairly devastating disease," but in general,
Ebola patients who survive without organ damage
are expected to "make a complete recovery," he
said.
Brantly and Writebol's releases are historic, says
CNN chief medical correspondent Dr. Sanjay
Gupta. They were the first humans with Ebola to
ever arrive in the United States. And they were
the first humans to receive an experimental Ebola
drug called ZMapp, which may have saved their
lives.
Treating Ebola
There is no known cure for Ebola, no proven
treatment and no vaccine. Treatment consists of
giving fluids, monitoring vital signs and
responding to acute medical crises. Symptoms
include fever, aches, diarrhea and bleeding.
Left untreated, infections can be
deadly in up to 90% of cases. But
around half the patients receiving
medical care in the current outbreak in
Liberia, Sierra Leone, Nigeria and
Guinea are surviving.
The Ebola virus spreads via direct
contact with bodily fluids, like blood,
sweat and feces. For Ebola patients to
leave isolation, Ribner said, two blood
tests done in a two-day period must
come back negative.
There is a slight possibility that the
virus could linger for up to three
months in vaginal fluid and semen ,
according to the World Health
Organization. Ribner said that there is
no evidence Ebola has ever been
transmitted in this way but that the
risk was discussed with both patients.
Asked about the role the experimental
drug may have played in their recoveries, Ribner
said doctors "do not know whether it helped
them, whether it made no difference" or whether
it might have delayed their recovery.
ZMapp was also given to three health care
workers -- two doctors and one nurse -- in
Liberia. The nurse and one of the doctors have
shown "a marked improvement," according to the
World Health Organization. The condition of the
second doctor is "serious but has improved
somewhat."
More human cases must be analyzed to
determine whether the drug is having a significant
effect or if it will help others in the region. But
"according to the manufacturer, the very limited
supplies of this experimental medicine are now
exhausted," the WHO said in a statement
Thursday.
Are they now immune to Ebola?
A deadly outbreak
More than 1,350 people have died in the West
African Ebola outbreak since the first cases drew
attention in March, the WHO said Wednesday .
Aid workers are fighting an uphill battle to stop
the disease as it continues to spread. Financial
and human resources have been stretched.
An emergency research "all call" was issued
Thursday by medical charity Wellcome Trust and
the United Kingdom's Department for International
Development to find a drug to stop the outbreak.
They are making $10.8 million available to fund
research. Wellcome Trust is committing another
$66.5 million to the development of health
research scientists in Africa, who are studying
many deadly diseases there.
Canada's public health agency had 800 to 1,000
doses of a vaccine known as VSV-EBOV delivered
to health officials in Liberia last week. It's
unclear if anyone has been given the vaccine.
But there has been a glimmer of hope: The World
Health Organization has seen "encouraging signs"
from Nigeria and Guinea that positive action can
rein in the deadly disease.
The situation in Lagos, Nigeria, where the
country's first case was detected in July, "looks
reassuring," the WHO said.
"At present, the city's 12 confirmed cases are all
part of a single chain of transmission. Those
infected by the initial case include medical staff
involved in his treatment, a patient in the same
hospital, and a protocol officer in very close
contact with the patient," the organization said.
One of those 12 has made a full recovery, the
WHO said, which "counters the widespread
perception that infection with the Ebola virus is
invariably a death sentence." Evidence suggests
early detection and therapy can help people
survive, it said.

ISIS: What it will take to beat terror group

(CNN) -- "We need long-term to take out ISIS'
leadership, to degrade their operational
capabilities, to cut off their financing sources, to
go after them in a comprehensive way to cut off
their ability to do the things we've seen them do."
Those were the words of State Department deputy
spokeswoman Marie Harf on Monday --
suggesting the Obama Administration is preparing
to do much more against the Islamic State in
Syria and Iraq than deprive it of the Mosul Dam.
They sounded much like the checklist used to
degrade al Qaeda over a decade.
Until the sudden capture of Mosul in June, ISIS
was of concern to Western governments but not a
pressing priority. Since then, the threat to
Baghdad, the plight of the Yazidi minority in
northern Iraq, direct threats to U.S. interests and
citizens and now the gruesome execution of
American journalist James Foley have galvanized
an unlikely coalition.
Iran, Saudi Arabia, the United States and Jabhat
al Nusrah, the al Qaeda affiliate in Syria: all have
the same adversary.
On Wednesday, President Obama said:
"There has to be a common effort to
extract this cancer so it does not
spread." French President Francois
Hollande concurs. In an interview with
Le Monde Wednesday he called for a
"comprehensive strategy against this
structured group, which has access to
substantial funding and to very
sophisticated weapons, and which
threatens countries such as Iraq, Syria
or Lebanon."
The first step in taking down al Qaeda
central was the invasion of
Afghanistan to deprive it of living
space. This time, the United States
hopes others -- specifically the
Kurdish Peshmerga and Iraqi armed
forces -- will do that part of the job
against ISIS, with a little help from
U.S. drones and F-16s.
Even so, killing off an organization
that is now much more potent than al
Qaeda or its affiliates will depend on a
lot of things going right in a region
where much has gone wrong.
Here are just a few of the challenges.
1. ISIS has considerable territory
In eight months, ISIS has taken control of
swathes of western and northern Iraq, and
expanded its presence in northern Syria. For
hundreds of miles along the Euphrates and Tigris
rivers, ISIS is the power in the land; it now holds
an area larger than the neighboring state of
Jordan. While al Qaeda never really held territory
beyond training camps and caves in remote parts
of Afghanistan, ISIS controls cities (Mosul, Tikrit
and Tal Afar in Iraq; Raqqa in Syria) and oil
fields, main roads and border crossings. And it
possesses more military hardware than some
national armies after seizing both Iraqi and Syrian
military bases and armories.
Critically, ISIS is able to use both
Syrian and Iraqi soil in a much more
muscular way than al Qaeda and the
Taliban used the mountain tracks
between Pakistan and Afghanistan.
This gives it tactical flexibility and
safe havens. Although its Syrian
strongholds have come under aerial
attack recently by the Syrian air force,
the group retains control of Raqqa
and Deir Ezzour provinces in the north and east of
the country, and has in recent days seized villages
close to Aleppo, some 250 miles from the border
with Iraq. It also holds villages and towns along
the Syrian border with Turkey.
As ISIS threatens to overwhelm other rebel groups
(see below), especially the remnants of the Free
Syrian Army, one critical factor will be the Syrian
regime's tactics. Until recently it has focused its
fire on other groups in securing Damascus and
retaking Homs. There are signs it now sees ISIS
as a clear and present danger; ISIS has seized
several military bases in Raqqa province, and
threatens to take the important Tabqa air base.
In the last week, the Assad regime has stepped
up its use of air-strikes against ISIS, no doubt
aware of the coincidental benefit of showing the
West that Syrian help is required to tackle ISIS.
ISIS could be squeezed from several directions,
but it would require co-ordinated commitment
from Syria -- which has other battles to fight and
may still see ISIS as a useful counterbalance
against other rebel groups -- as well as the Iraqi
army and the Kurds. Desperation has led Baghdad
to co-operate with the Kurds. Whether that is
sustainable is open to question.
2. ISIS has men, money, munitions
Unlike most jihadist groups, ISIS has
some serious weaponry and plenty of
seasoned fighters. In an assault on a
major Syrian army base earlier this
month, ISIS deployed three suicide
bombers and dozens of well-armed
fighters. A long battle ended with the
fall of the base (one of the last held
by the regime in Raqqa) and --
according to Syrian activists -- the
summary execution of dozens of
soldiers.
It was symbolic of ISIS' ability to
conduct complex operations
simultaneously in theaters hundreds of
miles apart. The Syrian Observatory
for Human Rights claims ISIS gained
6,300 new recruits -- 80 percent of
them Syrian and the rest foreign -- in
July alone. While U.S. officials say the
number of active fighters probably
numbers some 15,000, Iraqi analysts believe ISIS
may be able to field three times that number.
A significant number are from Europe, Australia
and the former Soviet Union. On Wednesday,
Austrian prosecutors said nine people had been
arrested on suspicion of intending to join Islamic
militants in Syria, the latest indication of the
stream of radicalized young Muslims lured to the
promised land.
ISIS paints a picture of this land through a
sophisticated outreach program on social media
and through its English-language online
publication, Dabiq, which is full of accounts of the
coming showdown with "crusader armies,"
appeals to Muslims to come to the Islamic State
and promises that "it is only a matter of time and
patience before it reaches Palestine to fight the
barbaric jews."
The aim of creating a Caliphate gives
the group a mission that appeals to
many young jihadists in Syria, Iraq
and beyond. It's a goal that gives
ISIS' campaign religious underpinning,
and is constantly referred to in the
group's literature.
ISIS has shown a ruthless discipline
in its military tactics, forcing the Iraqi
military to fight on several fronts at
once and using mobile groups of a few dozen
fighters as a first wave in attacking targets. It has
a well-deserved reputation for accepting
casualties in the pursuit of an objective and uses
probing operations to test defenses (as in Mosul)
and to keep opponents off-balance. In July, ISIS
fighters attacked gas installations in Homs
province, which diverted Syrian forces, only to
then launch more concerted assaults on targets
further east.
According to the Institute for the Study of War
(ISW) , which follows ISIS' campaign closely, "the
breadth of these linked offensives across Iraq and
Syria illustrate the ISIS priority objective of
establishing territorial integrity for the Caliphate,
and are evidence of the large military capacity
ISIS still possesses nearly two months after the
fall of Mosul.
"As continued military successes from
increasingly unified theatres of operation fuel the
ISIS war machine, a hardened ISIS exterior line is
likely to allow ISIS forces to pursue further
expansion," ISW says.
ISIS control of border crossings is a source of
revenue, as are bank raids in the towns and cities
they have seized. The group has seized oil
refineries, and may make as much as $2 million a
day from its control of fuel supplies in northern
Iraq . They also hold the al-Omar oilfield in Raqqa.
3. ISIS is strangling the Syrian rebels
Perhaps the most immediate -- and
most difficult --- challenge in
reversing the ISIS tide is preventing it
from killing off what remains of the
more moderate Syrian opposition to
Bashar al Assad. Already driven out of
Homs through starvation, these
groups are now caught between the
hammer of ISIS and the anvil of the
Syrian army in and around Aleppo.
ISIS is closing in on Aleppo from the
north , while the regime cuts off other
routes.
Brian Fishman, who has followed the rise of ISIS
longer than most, says that supporting the Free
Syrian Army earlier might have blunted ISIS, "but
that's a pretty hollow position if one also gives
Syrian rebel factions a pass for tolerating and
even embracing ISIL and Jabhat al-Nusrah
through late 2012."
The remnants of the Free Syrian Army are
disjointed and deflated -- and deeply resentful of
failed western promises to provide the sort of
military aid that would have tipped the military
balance. Elements of the anti-ISIS Islamic Front
are also starved of resources, and even Jabhat al
Nusrah, the al Qaeda affiliate in Syria, has shifted
its focus rather than take on ISIS.
After its gains north of Aleppo, ISIS may also be
able to extend its control to parts of the Syrian-
Turkish border, cutting off resupply routes for
other groups. Syrian activists say ISIS fighters are
now just a few miles from the town of Azaz, close
to the border.
Can the U.S. and its partners help revive Syrian
rebels to the point they can take on ISIS before
the military balance in Syria tips decisively
against them?
The record is not encouraging. Exactly three years
ago, President Obama said the United States
would lead the effort in "pressuring President
Assad to get out of the way of this [democratic]
transition, and standing up for the universal rights
of the Syrian people - along with others in the
international community."
Assad is still standing. The rebels are
in disarray. And the Syrian people can
only imagine what universal rights
might look like.
4. ISIS hasn't over-reached as yet.
But there are signs
Much of ISIS' success has derived
from its ability to strike local deals
with Sunni tribes in both Syria and
Iraq -- either in the face of a common enemy or
because tribal leaders see opposition as futile
and/or suicidal. In Syria, for example, ISIS
commanders co-opted the Sharabia tribe in joint
operations against local Kurds.
It has shown merciless cruelty to enemies,
beheading Syrian soldiers and executing Shia
civilians and soldiers in Iraq. Displaying severed
heads and other draconian demonstrations of
ruthlessness are calculated to create a climate of
fear among would-be adversaries. Human Rights
Watch noted reports this week that ISIS had
"executed as many as 700 members of the
Sheitaat tribe in Deir al-Zour governorate, many
of them civilians."
This ruthlessness is the ultimate form of
totalitarian control -- but controlling such a vast
area is only possible with the acquiescence of the
civilian population. And this may change,
especially if the new Iraqi Prime Minister extends
an olive branch to the Sunni tribes; and if those
who would oppose ISIS, both in Iraq and Syria,
get support in the form of intelligence and
weapons and support from the air.
Dawn Chatty, a social anthropologist at Oxford
University, says that in north-eastern Syria "the
Bedouin are very hard to terrorize, and the
Bedouin will really come back." The head of the
Sheitaat tribe has already called on other groups
to join it in opposing ISIS.
But ISIS has shown itself to be smarter than its
equally ruthless predecessor, al Qaeda in Iraq,
which ultimately alienated Sunni tribes and led
them to sign up for the U.S.-sponsored
"Awakening" against extremism. It has provided
food, fuel and security to populations on the brink
of destitution after three years of civil war in
Syria. And as Yochi Dreazen notes in Foreign
Policy , ISIS "has generally allowed the local
bureaucrats in charge of hospitals, law
enforcement, trash pickup, and other municipal
services to stay in their jobs." Its sharia courts
have cut crime -- albeit more by cruel example
than by due process.
While Raqqa is the flagship of ISIS' model of
governance, there are other Syrian towns -- such
as al-Bab and Manbij -- where it has shown
organizational skills. Charles Caris at the Institute
for the Study of War says that "as ISIS takes sole
control over territory, it expands to provide more
services, often operating the heavy equipment
needed to repair sewer and electricity lines."
But running towns and dispensing
services is a costly business, and
there are only so many banks to
empty. As Caris observes: "The
immediate provision of aid and
electricity, for example, does not
translate into the creation of a durable
economy."
5. The Iraqi government still needs to
get its act together
In some ways, Iraqi Prime Minister
Nouri al Maliki was the best recruiting
sergeant ISIS could wish for,
repeatedly alienating the Sunni
minority with heavy-handed tactics against
dissent, followed by indiscriminate bombing when
ISIS took Fallujah in January. Maliki became
identified with a chauvinistic Shia outlook heavily
influenced by Iran.
Now Haidar al-Abadi -- the Prime Minister in
waiting -- has the opportunity to win back the
support of senior military commanders who had
become disillusioned with the way Iraq's security
forces had been so brazenly politicized, and lure
the Sunni tribes back into political process. And
that would starve ISIS of the "host" on which it
has thrived for the past few months.
Some Sunni tribal leaders have already make it
clear they will deal with al-Abadi, if the price is
right. Iraqi analysts say this price includes an end
to the allocation of ministries and other arms of
government purely on the basis of partisan
patronage.
The Kurds seem ready to give al-Abadi a chance.
Hoshyar Zebari has returned to his post as Iraqi
Foreign Minister in Baghdad, telling CNN's Becky
Anderson Wednesday: "We've rejoined the
caretaker government."
After the recapture of the Mosul Dam, the Iraqi
army has launched another attempt to retake
Tikrit. But so far ISIS is still in control of most of
the town. There is a long way to go before real
progress against ISIS can be demonstrated.
6. The international coalition needs
to stick together
The events of the last few weeks,
especially the horrendous brutality of
ISIS that has mobilized global opinion
and the existential threat to Iraq as a
state, has concentrated minds from
the Gulf to Europe and Washington.
"Suddenly, a common enemy has joined mutually
distrustful players in the making of a coalition
against ISIS -- just the kind of multilateralism
that the U.S. President favors," writes George
Packer in The New Yorker .
But does that coalition have willpower and
cohesion to pursue what will be a costly -- and
long-term -- mission? Will the U.S. be ready to
use greater military force in Iraq in support of
both the Kurds and the Iraqi military, including the
deployment of Special Forces, given that the
Obama administration sees ending the war in Iraq
as a major achievement? And will the new
government in Baghdad -- still likely to be a
largely Shia coalition -- make enough
concessions to both the Kurds and Sunnis to
rekindle the 'concept' of Iraq?
In Syria, will the friends of the opposition,
including the U.S., Turkey and the Gulf states be
ready to prioritize the goal of helping rebel
groups, including even Islamist elements, against
ISIS, over the long-term aim of removing al
Assad? Time is short.
Frederic Hoff of the Atlantic Council argues that
"if, for example, the [opposition] Coalition were to
establish itself in northern Syria, its associated
military elements would need -- among other
things -- the means to neutralize regime military
aviation and ISIS ground forces." That's a lot of
means.
Some former US military officials have spoken of
the need to put 10,000 to 15,000 US troops on
the ground to "roll back" ISIS. Brian Fishman, a
Fellow at the New America Foundation, writes in
War On the Rocks that "10,000-15,000 troops
vastly understates the true commitment, which
will actually require years, direct military action
on both sides of the Iraq/Syria border, tens (if not
hundreds) of billions of dollars, and many more
than 15,000 troops."
And Fishman takes a pessimistic view of the
prospects of getting rid of ISIS any time soon.
"The political consensus to incur the risks and
costs of destroying ISIS is tremendously unlikely.
And even then, success hinges on dramatic
political shifts in both Iraq and Syria that under
the best of circumstances will require years."
Which is where we started: the "long-term." And
even then.

The Blast

This wasn’t Talib Kweli’s first time on CNN, but
it’ll probably be his last. During his interview
with Don Lemon in Ferguson, MO Talib argued
that CNN was mishandling the narrative of the
Mike Brown protests. He even accused Don of
being rude when they met. Eventually, they came
to some common ground and shook hands.
Reality TV indeed.

El Classico: When stars collide

There are few sporting contests that carry quite the
same passion as a Real Madrid-Barcelona clash.
Their meetings regularly captivate millions of fans,
not only in their homeland but across the
footballing world.
As the big day approaches, countless Spaniards,
including many who would ordinarily be immune
from the charms of the beautiful game, get swept
along by the fervour of the big event and don the
colours of their favourites.
Over the last decade, with the Galactico era in
Madrid and the dominance of European club football
by Barça, a number of world champions have faced
off. These star names include Roberto Carlos, Fabio
Cannavaro and Zinedine Zidane for Los Blancos as
well as Ronaldinho and some of the stars of
Spain’s FIFA World Cup-winning side of 2010: Xavi,
Andres Iniesta and Gerard Pique.
However, it is not just in recent times that the
teams have had such a glittering array of stars at
their disposal. Down the years some of the greatest
players ever to grace the sport have taken the field
for the big two, including Di Stefano, Ferenc Puskas,
Santillana, Hugo Sanchez, Emilio Butragueno and
Michel for Madrid, and among others Ladislao
Kubala, Luis Suarez, Johan Cruyff, Diego Maradona,
Hristo Stoichkov, Ronald Koeman, Rivaldo and
Romario for the Blaugrana.
Side swappers
And there is another even more exclusive list of
players worth mentioning, those who took the brave
decision to take the Puente Aereo (the route
connecting Barcelona and Madrid) and swap clubs.
Di Stefano, Bernd Schuster, Michael Laudrup, Luis
Enrique, Luis Figo and Ronaldo are just some of the
stars who broke the hearts and invoked the wrath
of their former supporters, for whom changing
allegiances is an act of unforgivable treason.
Real Madrid-Barcelona games have produced more
than their share of anecdotes, amazing results,
legendary performances and enmity ever since the
pair first crossed swords in 1902, a match the
Catalan side won 3-1. The first league meeting
came in 1928, when the Merengues inflicted a
painful defeat on the Blaugrana in their own back
yard.
Six years after their 1928 encounter, Real Madrid
trounced the Cules 8-2 in a 1935 league match in
the capital, although Barcelona, led by Hungarian
Ladislau Kubala, would exact a measure of revenge
by walloping their foes 7-2 in front of their home
fans in 1950.
The Di Stefano derby
In 1953 the two sides were in confrontation again,
this time in a battle to secure the services of Alfredo
Di Stefano. One month after the dispute was settled
in favour of the capital side, the legendary Argentine
they called the Blonde Arrow began a love affair
with the fans of the Bernabeu by scoring twice in a
5-0 thrashing of the old enemy.
Twenty years on in 1974, with Dutchman Rinus
Michels at the helm and his compatriot Johan
Cruyff at his mercurial best, it was the turn of the
Blaugrana to post a 5-0 scoreline, and at the
Bernabeu for good measure. Two decades later
Cruyff, by then Barça coach, presided over another
5-0 drubbing, as his Dream Team lorded it over
their rivals at the Camp Nou, with Romario running
Francisco Buyo ragged and scoring an exquisite
hat-trick.
Barely 12 months later at the Bernabeu and the
shoe would be on the other foot. This time it was
the visiting keeper Carles Busquets (father of
Sergio) who had his goal breached five times, with
a hat-trick form Chile's Ivan Zamorano doing most
the damage. The game was also notable for the
presence in the victorious Madrid side of Michael
Laudrup, a player who just a year earlier had played
for Barça in their famous 5-0 at the Camp Nou.
A decade down the road, fans of the Merengues
were certainly made to suffer at the hands of their
greatest rivals. Not only did they have to watch as
their sworn enemies claimed both the Spanish and
UEFA Champions League titles, but they felt honour
bound to stand and applaud an inspired Ronaldinho
after his two wonder-goals helped Barça to a 3-0
win at their stadium.
After the Brazilian’s departure, it was the turn of
Lionel Messi to take the famous Barça No10 shirt.
The little Argentinian scored his first Clasico goals
in March 2007, grabbing a Camp Nou hat-trick in a
pulsating 3-3 draw. Cristiano Ronaldo, his Madrid-
based rival, has had his own say in this fixture in
the past, scoring an extra-time headed winner in
the 2011 Copa Del Rey final.
El Clasico has developed into world football’s most
hotly-anticipated derby match. Whenever the two
meet, the world grinds to a halt to watch the stars
collide.

Jackie Chan responds to son's drug bust: 'I'm extremely furious'

Hong Kong (CNN) -- Kung fu movie star Jackie
Chan says he "takes responsibility" for the drug
charges laid against his son, 32-year-old Jaycee
Chan, in Beijing.
Police detained the junior Chan, who is originally
from Hong Kong and also an actor, as well as Kai
Ko, a 23-year-old Taiwanese actor, during a raid
on August 14 in Dongcheng district, Beijing, state
media said.
Both men tested positive for marijuana.
READ: Jackie Chan's son held in anti-drugs
crackdown in China's capital
Jackie Chan publicly addressed the incident for
the first time on Wednesday evening, through
messages posted on his account on Weibo, a
Chinese microblogging platform.
The star of "Rush Hour" wrote that he felt
"extremely furious" and "extremely shocked" at
the news of his son's drug woes, adding that
Jaycee's mother is "heartbroken."
"I hope that young people will see Jaycee as a
cautionary tale and stay away from drugs," wrote
Chan, who once campaigned against drug use
and was named an anti-drugs ambassador in
China in 2009.
"I failed to teach my son and I should also bear
responsibility. Jaycee and I deeply bow in apology
to society," concluded Chan on his Weibo, which
has more than 23 million followers.
'Really sorry'
After detaining the young actors, police searched
Jaycee Chan's apartment and found more than
100 grams of marijuana. He was also accused of
"hosting others to take drugs," the state-run
China Daily said. He could face three years in jail
under Chinese law.
State broadcaster CCTV aired footage of Chan,
his face blurred, showing police where the drugs
were hidden at his home, while Ko was shown
making a tearful apology.
"I very much regret what happened. I'm very
sorry to those who support me, like me or even
know me personally," he said. "I just want to tell
them I'm really sorry. I've set the worst example,
which had the most terrible influence. And this is
a huge mistake."
Celebrity targets
The two actors are being seen as the targets of
the capital's latest anti-drugs campaign, which
has snared more than 7,000 people for using
drugs since January, a 72% year-on-year
increase, according to China Daily .
Celebrities are increasingly in the spotlight, with a
number of high-profile arrests over drug-related
incidents in recent months, including popular
movie actor Zhang Mo and singer Li Daimo, who
was sentenced to nine months in jail for hosting a
crystal meth party at his home, according to the
China Daily.
Earlier this month, dozens of management
agencies representing performers in the
entertainment industry signed an agreement with
Beijing authorities banning drug use from the
industry and pledging to sack artists who break
the law.

Robots kidnap a human in the first trailer for dark sci- fi film 'Automata'

With just its first trailer, Automata easily takes a
place beside Christopher Nolan's Interstellar on
the list of the best-looking sci-fi films coming this
year. The film takes place in a dark future where
robots are quickly gaining consciousness, and
things go bad when a small number of them
actually become sentient and kidnap a human.
What really is sentience and humanity and true
thought? Sure, these questions have all been
explored before, but with its Blade Runner -esque
vision and District 9- kind of grittiness, it looks
like Automata will have an interesting take on it
all. Plus, Javier Bardem plays a robot, which is
pretty great. It'll be released on October 10th.

Nurse arrested for stealing penises

Lagos - The 52-year old was arrested in the
Croatian town of Slavonski Brod on suspicion of
possessing human body organs.
Local police raided the suspects' apartment
where they found numerous human penises
soaking in formaldehyde. The solution stopped
the organs from rotting.
As a nurse, the suspect had easy access to the
hospital morgue where police believe he severed
the penises from deceased males and took
them home.
Also Read: Infertile men might need 'sperm
shield' boost
Slavonski Brod is a mid-sized town of 59 000
and has been inhabited since prehistoric times.
Speaking to Queerty.com, hospital spokesman
said "On behalf of all employees of the hospital,
I have to say that we are very unpleasantly
surprised by an event that threw a shadow over
this hospital. Our apologies to the families of
the deceased."
The man had no prior criminal record and was
described by police as a "family man." It
remains unclear what the suspect intended to
use the penises for. He is currently on bail
pending his trial for disturbing the deceased. If
he is found guilty, he could face up to two
years in jail.
- Health24

PDP allerges Amaechi bribed Rivers state judiciary

Lagos - The spat between the People’s
Democratic Party (PDP) and Rivers State
Governor, Rotimi Amaechi, took a new twist
after the party accused the premier of inducing
legal professionals with computers to prolong
their strike.
PDP alleged Amaechi had distributed a total of
250 laptops to members of the Nigerian Bar
Association (NBA) of the Bori, Ahoada, Isiokpo
and Degema branches.
The party said the governor also promised to
release additional 1 000 laptops to members of
the Port Harcourt branch of the NBA.
Also Read: Sultan cautions politicians against
unguarded comments
The ruling party, which nonetheless plays
second fiddle to the All Progressive Congress in
the state, said it condemned the governor's
“Greek gift” as it was ill-timed and ill-
motivated.
“If the governor believes that lawyers in the
state deserve a gift of laptops, then it is
certainly not appropriate, considering the
manner and circumstances surrounding the
distribution of the laptops, and to do so at this
point in time when efforts should be dissipated
at ensuring that the courts resume sittings
makes it more suspicious. There is no doubting
the fact that Governor Amaechi’s intention is to
lure the lawyers in order to cage them from
opposing his many pranks and acts of impunity
against the judiciary in the state,” the party
said in a statement.
Also Read: Council boss slumps, dies in Rivers
The PDP said its holds the law profession, as
well as some members of the bar in high
esteem and believed no amount of gifts by
Governor Amaechi, who could not be reached
for comment, would make them err.
“The PDP continues to hold Governor Amaechi
responsible for this embarrassing situation in
the judiciary, while calling on lawyers to remain
focused and resolute in their stance against all
forms of impunity by the administration of
Governor Chibuike Rotimi Amaechi,” it said.
– CAJ News

Obama Mourns Journalist: Islamic State 'Has No Place in the 21st Century'

n one of his most forceful denunciations of
Islamic State militants to date, President Barack
Obama on Wednesday condemned the group's
barbaric beheading of an American journalist.
"The entire world is appalled by the brutal
murder of Jim Foley," Obama said in his first
remarks since the release of the gruesome online
video by the Islamic State (also known as ISIL
or ISIS).
Despite his outrage, Obama gave no indication
that he planned to curtail airstrikes against
Islamic State fighters in Iraq, even as the
militants threatened the life of a second hostage
journalist unless the U.S. changed course.
The president appeared angered and grim as he
spoke from Martha's Vineyard, where he is
vacationing. He said he had talked to the
journalist's family and told them that "we are all
heartbroken for their loss."

West Africa must confront political weaknesses to curb drugs trade -Obasanjo

Accra - West Africa must openly confront its
political and governance weaknesses to curb the
growing drug trade in the region, former President
Olusegun Obasanjo said on Wednesday.
"West Africa is no longer only a transit zone of
drugs but an attractive destination where pushers
take advantage of the weak political system to
perpetuate their trade," Obasanjo, who chairs the
West Africa Commission on Drugs (WACD), said
while presenting his report to Ghana's President
John Mahama.
"We believe that we should confront openly the
political and governance weaknesses which the
traffickers exploit," Obasanjo said.
Also Read: West African experts call for drugs
decriminalisation
Former United Nations chief Kofi Annan set up the
commission last year to explore ways to stem the
increasing trafficking of drugs and its use in the
region.
West Africa has long produced and consumed
cannabis but its collection of weak states has
over the last decade become a major transit zone
for Latin American cocaine destined for Europe.
Heroin from Asia is also passing through the
region.
Drugs are undermining the stability of West
African countries and their development, "eating
not only into the normal life of our youth, but it's
eating into our political system and governance,"
Obasanjo said.
In its report released in June, the commission
called on governments in West Africa to
decriminalise drug use and treat the issue as a
health problem.
Obasanjo said because of the amount of money
involved, "drug barons can buy, they can do, and
they can undo - buy officials in the military,
security and pervert justice."
Annan said wrong-headed governmental policies
by leaders and influential people in society have
destroyed many more lives in West Africa than
drug use.
WACD has 11 members including former
President Pedro Pires of Cape Verde and former
Togolese Prime Minister Edem Kojo.